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Unurjargal, Tsolmon

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Товч нэр
Unurjargal, Tsolmon
Бүтэн нэр
Unurjargal Tsolmon
Латин нэр
Unurjargal Tsolmon
Албан тушаал
Судлаач
Харьяалал
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    Item type:Publication,
    Utilizing natriuretic peptides for predicting heart failure risk following myocardial infarction
    (2025-09)
    Ulziisaikhan, Ganchimeg
    ;
    Khurelbaatar, Mungun-Ulzii
    ;
    Khorloo, Chingerel
    ;
    Khasag, Altaisaikhan
    ;
    Unurjargal, Tsolmon
    BACKGROUND: In Mongolia, ischemic heart disease, specifically acute myocardial infarction (AMI), is a significant etiology of chronic heart failure (HF). Therefore, early recognition of the risk of HF following AMI is critically important for improving patient management. This study aimed to assess the N-terminal pro-B-type natriuretic peptide (NT-proBNP) as an early detection and prognosis of asymptomatic left ventricular (LV) dysfunction following AMI. METHODS: Patients diagnosed with AMI and in the absence of symptoms or signs of HF were prospectively included. Clinical and echocardiographic data were collected at baseline, and NT-proBNP levels were measured at admission and discharge. Patients were divided into four distinct groups based on NT-proBNP level quartiles. The study endpoint was de-novo HF at 6 months after AMI. RESULTS: A total of 120 patients with a mean age of 56.0 ± 9.2 years and 80.8% (N = 97) men were included. Higher NT-proBNP levels were associated with elevated GRACE score and diabetes, both at admission and predischarge. Additionally, higher NT-proBNP levels at admission were associated with delayed hospital presentation, whereas higher NT-proBNP levels at predischarge were associated with reduced LV global longitudinal strain. Furthermore, NT-proBNP level at predischarge was significantly associated with the development of HF 6 months after AMI, with a threshold value of 1410 pg/ml. CONCLUSION: Incorporation of NT-proBNP measurement before discharge in AMI patients could enhance risk stratification, thereby supporting its integration into routine clinical evaluation for more efficient patient management.
    Scopus© Citations 1