Jamiyanjav, Baasankhuu

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Aspects of Diagnosis and Treatment of Retinoblastoma in Mongolia
(Mongolian National University of Medical Sciences, 2018-06-25)
Chuluunbat, Tsengelmaa
;
Munkhuu, Bayalag
;
Bazarsad, Uranchimeg
;
Molom, Altankhuu
;
Jamiyanjav, Baasankhuu
Objectives: To describe the clinical characteristics and the treatment outcome of retinoblastoma in Mongolian children. Methods: Data of all children diagnosed with retinoblastoma at the National Center for Maternal and Child Health of Mongolia from 1987 to January 2017 were reviewed retrospectively. The ICRB classifi cation was used. Survival characteristics of the cohort were analyzed. Results: Retinoblastoma was diagnosed in 100 eyes of 79 children during the study period. Median age of diagnosis was 23.2±5.8 months. There were no differences in sex ratio and 21 cases (27%) were bilateral. Fifty-two patients (66%) were from rural areas. The more frequent clinical presentations were leukocoria in 64 (81%) patients, unilateral mydriasis 35 (45%) and strabismus in 34 (44 %) patients. Sixty-nine (87.3%) patients were diagnosed with Classifi cation D or worse when presented to us. Due to late diagnosis in the majority of cases, unilateral and bilateral enucleations were performed in 58 (58%) eyes and 26 (26%) eyes respectively; exenteration was done in 3 (3%) eyes, intravenous chemotherapy was done (11%) eyes and laser surgery was done (4%) eyes. After the mean follow up of 10 years, 67 (84.8%) patients were alive, 5 (6.3%) patients died and in 7 (8.8%) patients their vital status was unknown. The mean follow-up period was 144.1±16.3 (95% CI 122.6-165.5) months (range, 15-365months). In 5 cases in which immunohistochemistry analysis was performed, neuron-specifi c enolase (NSE), Ki-67 protein (Ki-67), B-cell lymphoma 2 (Bcl-2) positive cells were found in all of 5 (100%) cases and Rb protein was detected in 3 (60%) cases. Conclusion: The implementation of International Classifi cation of Retinoblastoma, systemic intravenous chemotherapy and laser treatment for retinoblastoma, shows favorable outcome in the treatment of retinoblastoma and further prognosis.
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Anatomy of lacrimal sac fossa affecting success rate in endoscopic and external dacryocystorhinostomy surgery in Mongolians
(Korean Association of Anatomists, 2021-12)
Purevdorj, Bayasgalan
;
Dugarsuren, Uranchimeg
;
Tuvaan, Bulgan
;
Jamiyanjav, Baasankhuu
To study the affect of anatomical variance of lacrimal sac fossa on dacryocystorhinostomies (DCR) performed by the traditional external (EX-DCR) approach or an endoscopic (EN-DCR) endonasal approach. A total of 292 consecutive cases with primary nasolacrimal obstruction underwent DCR surgery. Orbital computed tomography scan was used to measure lacrimal sac fossa and other related structures and Lac-Q questionnaire was used to compare surgery result. Maxillary portion of lacrimal sac fossa is thicker in failed surgery group than successful surgery group (P<0.05). Lateral nasal structures (uncinate process, operculum of the middle turbinate, agger nasi) are dominantly adjusting to lacrimal sac fossa in failed surgery group (P<0.05). Patients who underwent EX-DCR has a 6.0-point and EN-DCR group 11.0-point improvement (P<0.016) in Lac-Q questionnaire. Patients who have a thick frontal process of the maxilla and uncinate process, operculum of the middle turbinate, ethmoid cells adjusting to lacrimal fossa are prone to have recurrence of nasolacrimal duct obstruction after DCR surgery. The EN-DCR and the EX-DCR approach have an equivalent surgical success rate but improvement in quality of life by using the Lac-Q questionnaire is greater in the endoscopic group when compared with the external.
Scopus© Citations 9
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Retinoblastoma in Mongolia: Clinical characteristics and survival from 1987 to 2014.
(2016)
Chuluunbat, Tsengelmaa
;
Jamiyanjav, Baasankhuu
;
Munkhuu, Baylag
;
Bazarsad, Uranchimeg
;
Molom, Altankhuu
Scopus© Citations 7

Jamiyanjav, Baasankhuu

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