Nanzadsuren, Tuya

Now showing 1 - 1 of 1

Some of the metrics are blocked by your
consent settings
Association between serum melatonin and skin aging in an urban population of Mongolia
(Wiley, 2020-06)
Nanzadsuren, Tuya
;
Myatav, Tuul
;
Dorjkhuu, Amgalanbaatar
;
Byamba, Khandsuren
BACKGROUND: Melatonin has been implicated in skin functions such as hair growth cycling and skin pigmentation. Furthermore, melatonin receptors are expressed in several skin cells. AIMS: To study the association between serum melatonin levels and skin aging grades among people aged 20-69 years in Ulaanbaatar city. PATIENTS/METHODS: We performed an analytical cross-sectional study that used parametric testing through analyses to test the relationship between melatonin levels and skin aging grades. A total of 946 people were assessed for skin aging using a moisture checker, sebum tape, and a digital camera. Blood samples were collected between 8:00 am and 10:00 am, and melatonin was measured using an enzyme-linked immunosorbent assay analyzer. RESULTS: There was a statistically significant association between age and skin aging grade (P < .001). A multiple factor analysis revealed that lower levels of melatonin in the serum increased with skin aging grade 4 (odds ratio [OR], 1.9; 95% confidence interval [CI], 0.4-8.0), (OR, 2.4; 95% CI, 0.5-9.5), grade 5 (OR, 3.8; 95% CI, 0.8-15.7), and grade 6. There were weak associations between melatonin levels and potential covariates (skin pigmentation and skin hydration) taken from the correlation matrix. There was a weak positive correlation between skin pigmentation and age (r = .28), a weak negative correlation between skin pigmentation and sleep status (r = -.20), and a weak negative correlation between skin hydration and age (r = -.27). CONCLUSIONS: Serum melatonin decreases with age, indicating that its loss may stimulate the process of earlier skin aging.
Scopus© Citations 6

Nanzadsuren, Tuya

Filters

Settings

Sort By

Results per page