Ganmaa, Davaasambuu

Товч нэр

Ganmaa, Davaasambuu

Бүтэн нэр

Ganmaa Davaasambuu

Латин нэр

Ganmaa Davaasambuu

Албан тушаал

Судлаач

Харьяалал

Анагаахын Шинжлэх Ухааны Үндэсний Их Сургууль

ORCID

0000-0003-3388-8475

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Influence of vitamin D supplementation on fracture risk, bone mineral density and bone biochemistry in Mongolian schoolchildren: multicenter double-blind randomized placebo-controlled trial.
(2023-05)
Ganmaa, Davaasambuu
;
Khudyakov, Polyna
;
Buyanjargal, Uyanga
;
Tserenkhuu, Enkhtsetseg
;
Erdenenbaatar, Sumiya
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Additional file 2 of Estrogen metabolites in premenopausal women living in China, Mongolia, and the United Kingdom
(Figshare (United Kingdom), 2026-06-10)
Lauren C. Houghton
;
Davaasambuu Ganmaa
;
Isabel Dos Santos Silva
;
Roni Falk
;
Michelle L. Lui
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Additional file 3 of Estrogen metabolites in premenopausal women living in China, Mongolia, and the United Kingdom
(Figshare (United Kingdom), 2026-06-10)
Lauren C. Houghton
;
Davaasambuu Ganmaa
;
Isabel Dos Santos Silva
;
Roni Falk
;
Michelle L. Lui
Supplementary Material 3. Supplemental Table 1. Adjusted least square means for selected metabolites (pg/mL per mg of creatinine).
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Additional file 3 of Estrogen metabolites in premenopausal women living in China, Mongolia, and the United Kingdom
(Figshare (United Kingdom), 2026-06-10)
Lauren C. Houghton
;
Davaasambuu Ganmaa
;
Isabel Dos Santos Silva
;
Roni Falk
;
Michelle L. Lui
Supplementary Material 3. Supplemental Table 1. Adjusted least square means for selected metabolites (pg/mL per mg of creatinine).
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Additional file 1 of Estrogen metabolites in premenopausal women living in China, Mongolia, and the United Kingdom
(Figshare (United Kingdom), 2026-06-10)
Lauren C. Houghton
;
Davaasambuu Ganmaa
;
Isabel Dos Santos Silva
;
Roni Falk
;
Michelle L. Lui
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Additional file 2 of Estrogen metabolites in premenopausal women living in China, Mongolia, and the United Kingdom
(Figshare (United Kingdom), 2026-06-10)
Lauren C. Houghton
;
Davaasambuu Ganmaa
;
Isabel Dos Santos Silva
;
Roni Falk
;
Michelle L. Lui
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Additional file 1 of Estrogen metabolites in premenopausal women living in China, Mongolia, and the United Kingdom
(Figshare (United Kingdom), 2026-06-10)
Lauren C. Houghton
;
Davaasambuu Ganmaa
;
Isabel Dos Santos Silva
;
Roni Falk
;
Michelle L. Lui
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Influence of vitamin D supplementation on muscle strength and exercise capacity in Mongolian schoolchildren: a randomised controlled trial
(2024-03)
Ganmaa, Davaasambuu
;
Hemmings, Stephanie
;
Jolliffe, David A
;
Buyanjargal, Uyanga
;
Garmaa, Gantsetseg
OBJECTIVE: To determine whether weekly oral vitamin D supplementation influences grip strength, explosive leg power, cardiorespiratory fitness or spirometric lung volumes in Mongolian schoolchildren. METHODS: Multicentre, randomised, double-blind, placebo-controlled clinical trial conducted in children aged 6-13 years at baseline attending 18 schools in Ulaanbaatar. The intervention was weekly oral doses of 14,000 IU vitamin D3 (n=4418) or placebo (n=4433) for 3 years. Outcome measures were grip strength, standing long jump distance and serum 25-hydroxyvitamin D (25[OH]D) concentrations (determined in all participants), peak oxygen uptake (VO2peak, determined in a subset of 632 participants using 20-metre multi-stage shuttle run tests) and spirometric outcomes (determined in a subset of 1,343 participants). RESULTS: 99.8% of participants had serum 25(OH)D concentrations <75 nmol/L at baseline, and mean end-study 25(OH)D concentrations in children randomised to vitamin D vs. placebo were 77.4 vs. 26.7 nmol/L (mean difference 50.7 nmol/L, 95% CI, 49.7 to 51.4). However, vitamin D supplementation did not influence mean grip strength, standing long jump distance, VO2peak, spirometric lung volumes or peak expiratory flow rate, either overall or within sub-groups defined by sex, baseline 25(OH)D concentration <25 vs. ≥25 nmol/L or calcium intake <500 vs. ≥500 mg/day. CONCLUSION: A 3-year course of weekly oral supplementation with 14,000 IU vitamin D3 elevated serum 25(OH)D concentrations in Mongolian schoolchildren with a high baseline prevalence of vitamin D deficiency. However, this intervention did not influence grip strength, explosive leg power, peak oxygen uptake or spirometric lung volumes, either overall or in sub-group analyses.
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Dietary Nutrition, Gut Microbiota, and Health Status Across Geographically Diverse Populations in Mongolia: A Cross-Sectional Study
(2025-07)
Zhao, Zhixin
;
Zhao, Feiyan
;
Chimeddorj, Battogtokh
;
Sun, Zhihong
;
Tserenkhuu, Enkhtsetseg
Until recently, nomadic nomadism has been the dominant culture in Mongolia. Dietary patterns have evolved to fit this culture and ensure the health of people. This cross-sectional study was conducted to investigate the key role of dietary nutrition in maintaining the health of the Mongolian population and its impact on gut microbiota. Meanwhile, the correlations between the gut microbiota, dietary nutrition, and health status of the Mongolian population were explored. This study revealed distinct patterns in the dietary structures of urban and nomadic populations. During winter, urban populations consume more fruits, vegetables, and egg products, whereas nomads consume more dairy products. The intake of nutrients such as energy, protein, and carbohydrates, and blood indices such as blood glucose and total cholesterol (TC) of nomadic populations were found to be significantly higher than those of urban residents (p < 0.05), and these nutrients exhibited significant correlations with the blood indices. Furthermore, the influence of both region and season on the gut microbiota of the Mongolian population with regional disparities was greater than that of seasonal variations. In winter, the gut microbiota composition of nomadic populations differed significantly from that of urban populations, as evidenced by a decrease in Bacteroides, Phocaeicola, Phocaeicola vulgatus, Bacteroides uniformis, and Lachnospira eligens and an increase in Firmicutes, Alistipes, Dorea, Ruminococcus torques, and Dorea formicigenerans (p < 0.05). Additionally, lactic acid bacteria and Bifidobacterium sp. were abundant in the gut of the Mongolian population, which present promising opportunities for developing and utilizing unique probiotic resources in Mongolia. The study also found correlations between microbial species and blood indices, as well as nutrients, providing novel evidence to support the complex relationships between gut microbiota, nutrition, and health status in the Mongolian population. Overall, this study revealed significant differences in dietary nutrition, gut microbiota, and health status among geographically diverse populations in Mongolia and contributed to a deeper understanding of the complex interplay between gut microbiota, nutrition, and health among Mongolians.
Scopus© Citations 4
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Estrogen metabolites in premenopausal women living in China, Mongolia, and the United Kingdom
(2026-06)
Houghton, Lauren C
;
Ganmaa, Davaasambuu
;
Dos Santos Silva, Isabel
;
Falk, Roni
;
Lui, Michelle L
BACKGROUND: Breast cancer incidence is lower in women living in Asia than women living in North America and Northern Europe. However, large differences exist within Asia, for example, Mongolia's breast cancer rate is even lower than China's. Endogenous estrogens in Asian populations have been hypothesized to explain the disparity because of their strong positive correlations with breast cancer, though few studies have compared estrogen metabolites (EM) within Asia or between Asia and higher breast cancer risk countries. METHODS: We measured urinary concentrations of estradiol and estrone (parent estrogens) and 13 EM (non-parent estrogens) formed by irreversible hydroxylation at the C-2, C-4, or C-16 positions of the steroid ring in premenopausal women living in Ulaanbaatar, Mongolia (n = 282), Shanghai, China (n = 121), and the United Kingdom (n = 125). We performed analysis of variance (ANOVA) using a generalized linear model procedure to assess differences in hormone concentrations between British and Asian (Chinese and Mongolian), and Chinese and Mongolian. Exponentiated least square means were used to calculate percent differences. We compared differences in overall means adjusted for age, body mass index, and parity by country during the follicular, peri-ovulatory, and luteal phases. RESULTS: Total, parent, and non-parent estrogen concentrations were generally higher in British than Asian women, while the non-parent to parent ratio was lower. While parent estrogens appeared higher in Chinese compared with Mongolian women, differences did not reach statistical significance except for peri-ovulatory estrone; total estrogen metabolites in the 2-, 4-, and 16-pathways were higher in Mongolian than Chinese women. The non-parent to parent ratio was highest in Mongolian women followed by Chinese women, with British women having the lowest ratio. CONCLUSION: Total urinary estrogens, both parent and their metabolites, were higher in British compared with Asian women. Our data showing the ratio of non-parent to parent estrogens, possibility reflecting greater estrogen metabolism, in women living in Mongolia, with one of the lowest breast cancer rates globally, than in women living in China, and in Chinese compared with British women, are consistent with their relative breast cancer risks and suggestive of a potentially protective metabolic profile.

Ganmaa, Davaasambuu

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