Gunchin, Batbaatar
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Товч нэр
Gunchin, Batbaatar
Бүтэн нэр
Gunchin Batbaatar
Латин нэр
Gunchin Batbaatar
Албан тушаал
Судлаач
ORCID
Scopus Author ID
40 results
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Item type:Publication, Determination of Filaggrin Gene Single Nucleotides Polymorphisms in Patients with Atopic Dermatitis(Mongolian National University of Medical Sciences, 2017-02-25); ; ; Objectives: The protein, filaggrin, is important in barrier function and epidermal differentiation facilitation. Filaggrin gene (FLG) mutations have been identified as the cause of ichthyosis vulgaris (IV), and certain mutations have been associated with atopic dermatitis (AD). We aimed to investigate genetic polymorphism of FLG in Mongolian AD patients. Methods: FLG mutations were determined using sequence analysis in 46 AD patients and 12 IV patients. Severity of AD was assessed using the Scoring Atopic Dermatitis (SCORAD) index. Allergen specific IgE were determined from serum. Filaggrin expression in skin punch biopsy samples of AD patients was investigated using immunohistochemistry (IHC). Results: Several single nucleotides polymorphisms (SNPs) (1150C>T, 1741A>T, 1791C>T, 2181C>G, 2191A>G, and 2263G>A) were demonstrated in AD patients using sequence analysis. Total IgE levels were significantly associated with age (p=0.03) and duration of disease (p=0.02). Presence of SNPs and mixed allergen specific IgE was significantly correlated (p=0.02); 2 SNPs were significantly associated with food allergen specific IgE levels (p=0.009). 2263G>A SNP was significantly correlated with food allergen specific IgE (p=0.003) and a history of atopic diseases (p=0.03). Conclusion: New mutations or genetic polymorphisms with ethnic characteristics may be detected among Mongolians. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Construction of Lentiviral Vectors for CAR-T Cell Applications in Mongolia(Atlantis Press International BV, 2025); ; Bat-Itgel, Ulziisaikhan - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Treatment of Chronic HCV Infection with Direct Acting Antivirals(Mongolian National University of Medical Sciences, 2021-09-21) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Impact of HLA-A-B-DR Matching in Kidney Transplantation: Graft and Patient Survival During Five Years(Mongolian National University of Medical Sciences, 2016-06-25); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Result of Bortezomib Induction Therapy Prior to Stem Cell Transplantation in Newly Diagnosed Multiple Myeloma Cases in Mongolia(Mongolian National University of Medical Sciences, 2017-06-25) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Antibody response of Comirnaty vaccine in different immunocompromised groups during the COVID-19 pandemic(Oxford University Press (OUP), 2023-05-01); ; ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Impact of Booster Vaccination on Infection and Hospitalization Rates during the Mass Vaccination in Mongolia(Mongolian National University of Medical Sciences, 2025-09-30); ; ; ; Objective: Our study aims to evaluate the effectiveness of booster vaccination in preventing new COVID-19 infections and related hospitalizations among groups that received the primary vaccination series. Methods: Booster vaccination started on August 31, 2021, at recruitment in May 2022. By May 2022, 64% of the Mongolian population had received two primary doses of a COVID-19 vaccine, and 31% had received a booster dose. We followed 1,251 participants (459 males and 792 females, with a mean age of 41.5 ± 14.5 years [18–93], and a median age of 39.0 years) over six months, from the start of booster immunization on September 1, 2021, to February 28, 2022. We compared infection and hospitalization rates among vaccinated groups using logistic regression and calculated vaccine effectiveness (VE) for booster recipients with the formula: VE = 1 – (vaccinated rate/unvaccinated rate) × 100. Results: All participants received two doses of one of four vaccines used in the nationwide campaign. During the study period, we identified 449 new infection cases, accounting for 35.9% of all participants, and 150 subsequent hospitalizations, or 12.0% of the total. Participants who did not receive a booster demonstrated significantly higher infection rates compared to those who did. Booster vaccination provided notably better protection against new infections among frontline workers and reduced hospitalizations in high-risk groups. No significant differences were found in VE when comparing participants based on seroconversion after initial vaccination or the type of booster vaccine used.Conclusion: Therefore, we concluded that COVID-19 booster vaccinations effectively enhanced protection against new SARS-CoV-2 infections among frontline healthcare workers, government employees, and individuals at higher risk for severe disease, thereby reducing their risk of hospitalization. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Relationship of Human Personal Characteristics in the three Independent Stratification Systems(Mongolian National University of Medical Sciences, 2021-04-01); ; ; ; Objectives: We aimed to analyze theassociation between the biophysiological characteristics of body constitution and temperament type with Mongolian Traditional Medicine (MTM) constitution type to understand further and integrate the application of these stratification systems in clinical medicine. Methods: Body constitution type was classified using the body-mass index, temperament type was determined using personality test, and dominant MTM constitution type was determined in 287 active blood donors. Age, gender, and ABO blood groups were considered as additional biophysiological characteristics. The correlation between the biophysiological characteristics and the nature of their relationship was investigated using likelihood ratio and receiver operating characteristics analysis. Results: Obesity and body-mass index were related to aging, and donor’s age and Badgan expression rate were shown as a sensitive and specific classifier for obesity state. The relationship between Badgan dominant types of human constitutions practiced in Mongolian Traditional Medicine and melancholic temperament was established. Badgan expression was a sensitive and specific classifier for melancholic and phlegmatic temperament. Conclusions: Stratification of human subjects using the primary types of human constitutions practiced in Mongolian Traditional Medicine may be helpful in clinical research and application. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Elevated Ammonia Level as a Diagnostic Marker of Hepatic Encephalopathy(Mongolian National University of Medical Sciences, 2016-06-25); - Some of the metrics are blocked by yourconsent settings
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