Badarch, Bat-Ireedui

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Renal Dysfunction After Liver Transplantation: a Single Center Study
(Mongolian National University of Medical Sciences, 2021-12-31)
Batsaikhan Batsuuri
;
Fidel López‐Verdugo
;
Bat-Ireedui Badarch
;
Suvd Nergui
;
Ariunaa Togtokh
Objectives: Mongolia is known as one of the countries with a high prevalence of viral hepatitis infection and its related liver cirrhosis and HCC. Therefor, liver transplantation (LT) surgery increases from year to year in Mongolia. Our goal was to evaluate post-transplant renal dysfunction (PTRD) and to investigate the predicting factors for renal dysfunction after LT. Methods: The impact of graft ischemic time, peri- and postoperative blood product transfusion, perioperative hemodynamics, time to extubating, intensive care length of stay, incidence of chronic renal failure, and mortality and morbidity were examined alone and then as a combined outcome. Results: Early renal dysfunction was identified by measuring serum creatinine and glomerular filtration rate. In our investigation which was a study group of patients following liver transplantation (LT), the following renal dysfunctions were found: 39% of recipients in the study had renal dysfunction, while the rest had no renal dysfunction. The average creatinine level of the recipients who had a renal dysfunction after LT, was 0.825 ± 0.24 mg/dl and the glomerular filtration rate was 111 ± 36.3 ml/min, and statistically significant. Conclusion: Preoperative kidney function plays a crucial role for postoperative renal dysfunction.
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Living donor liver transplantation postoperative donor follow-up
(2022-11-14)
Bat-Ireedui Badarch
;
Munkhbold Tuul
;
Bayarbileg Ganbaatar
;
Tamir Sainbuyan
Background: Mongolia has the highest prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), and hepatitis D virus infection. The prevalence of HCV was 18.9%. Additionally, HBV infection was observed in 23.1% and 1.2% were coinfected with HCV and HBV in Mongolia. Mongolia has the highest HCC incidence in the world (78.1/100,000, 3.5* higher than China). Methods: Of the 156 intended living donors, who had applied for liver donation, living donor liver transplantation (LDLT) surgery was performed at First Central Hospital of Mongolia from September, 2011 to September, 2020. All donors were healthy adults and kin to the recipients. The in-hospital and follow-up data was acquired from the patient records and the Organ Transplantation Center of First Central Hospital of Mongolia. The living donor morbidity was graded according to the modified Clavien-Dindo classification system. Results: Therefore, LDLT was performed 156 donors, 91 male donors (57.9%). The median age of the donors was 32.79.03 years (range, 18-49 years). Most donors (151, 96.7%) donated the right lobe liver. The remnant volume of the right lobe of the liver donor is 713.7152.4 g (59.42%), the remnant volume of the remaining liver is 487 g (40.58%). The average duration of LDLT is 6 hours 38 minutes2 hours 2 minutes, and the intensive care bed is 5.42.4 days. Total bilirubin (1.18 mg/dL), alanine aminotransferase (ALT; 204.9 U/L), aspartate aminotransferase (AST; 224.07 U/L) increased from the first postoperative day of LDLT surgery in all donors, on the seventh day after surgery total bilirubin (0.82 mg/dL), ALT (50.84 U/L), AST (72.69 U/L) decreased too normal. All the donors have led a normal life after donation postoperation seventh-tenth day. Only one case had a complication Clavien-Dindo Classification Grade3b, which is portal vein stenosis. Totally five deliveries had during these 10 years. There was no postoperative mortality. Conclusions: As far the liver donor survival rate after liver transplantation in our hospital is 100% since the first transplantation. Living donor liver transplantation is relatively safe for donors and severe postoperation complication is rare.
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P.367: Outcomes of liver transplantation: A single-center experience. (First Central Hospital of Mongolia).
(Wolters Kluwer, 2024-09-01)
Bat-Ireedui Badarch
;
Batsaikhan Bat‐Erdene
;
Batsaikhan Batsuuri
;
Ganzorig Batjargal
;
Sergelen Orgoi
Methods: This study was conducted in Transplantation Center of the First Central Hospital of Mongolia between September 2011 and May 2023 on a total 200 patients have undergone liver transplantation. Results: There were 105 female patients out of 200, age between 18 months to 62 years old, and the average MELD score was 15±5.5, length of hospital stay were 31±13.94. These transplants were for liver (living donor=189, deceased donor=11, pediatric=7). The most causes of liver transplantation were liver cirrhosis due to HBV/HDV (59.5%), hepatocellular carcinoma (22.5%), primary biliary cirrhosis (5%), and only HBV related cirrhosis, alcoholic cirrhosis. There were 23(11.5%) biliary complication, 17 (8.5%) acute cellular rejection, hepatic artery thrombosis 2 (1%), and 3 cases retransplanted. The five year survival was 87%. Conclusions: This study provides the process of liver transplantation in First Central Hospital of Mongolia, and these positive outcomes support LT as an important therapy for end-stage liver disease and early hepatocellular carcinomas. Introduction: Liver transplantation (LT) is a main treatment of end-stage liver disease. Specially developing country like Mongolia has high prevalence of HBV, HDV, and hepatocellular cancer. Liver transplant is the second-most common solid organ transplant procedure in Mongolia. This study aimed to evaluate the efficacy of liver transplantation in the First Central Hospital of Mongolia.

Badarch, Bat-Ireedui

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