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    Effectiveness of Cognitive Behavioral Therapy on Multi-drug Resistant Tuberculosis Patients in Mongolia: 10 years experiences
    (Mongolian National University of Medical Sciences, 2024-06-30) ; ; ;
    Anuzaya Purevdagva
    ;
    Kyung Hyun Oh
    Objective: During multidrug-resistant tuberculosis (MDR-TB) treatment, patients face de­pression and anxiety. This study aims to evaluate the effects of cognitive behavioral therapy (CBT) on the psychological status and risk of loss to follow-up (LTFU) during MDR-TB treat­ment in Mongolia. Method: Eligible participants were randomly assigned to intervention and control groups. Intervention group participants underwent CBT, while control group par­ticipants received standard patient education. Psychological status was assessed before and after CBT. MDR-TB treatment outcomes were evaluated as internationally defined. Results: The study included a total of 83 patients. After CBT, depression and anxiety levels decreased by 12% and 16%, respectively, in the intervention group, whereas the control group showed a 4% decrease in depression and an 8.5% increase in anxiety levels. MDR-TB treatment outcomes revealed an 8% higher treatment success rate and a fivefold reduction in LTFU rate in the intervention group compared to the control group. In multivariable logistic regression, risk factors associated with increased LTFU were living alone (OR 12.7, p=0.031) and not being provided CBT (OR 16.1, p=0.040). Conclusion: Our study suggests that CBT not only alleviates these psychological challenges but also diminishes the risk of LTFU during treat­ment, leading to improved MDR-TB treatment success.
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    Effects of Alcohol and Tobacco Abuse on Multi-Drug Resistant Tuberculosis Treatment Outcome, Mongolia
    (2022-05-13) ;
    Naranzul Dambaa
    ;
    ;
    Abstract: Alcohol and tobacco use, and drug resistance have become key issues in TB care in Mongolia. Although the use of alcohol and tobacco in patients with multi-drug resistant TB (MDR-TB) has been identified, the relationship between MDR-TB treatment outcomes, alcohol and tobacco use has not yet been studied. Aim of study: To study effects of alcohol and tobacco abuse on MDR-TB treatment outcome. Methods: This is randomly assigned case control study. Patients, who enrolled in MDR-TB short regimen between 2020 and 2021, were participated in the study. Alcohol and Nicotine dependence was assessed by Nicotine dependence standard scale and AUDIT scale. Results: Of the 64 MDR-TB patients, 55% were male and the mean age of participants was 38.07±1.75 years. Based on AUDIT, 78% and 22% patients were classified as low risky, harmful, high risk level of alcohol use (Cronbach`s alpha 0.936). Conclusion: Alcohol and tobacco abuse are higher among MDR-TB patients in Mongolia. Alcohol and Nicotine dependence associated with bad treatment outcome of MDR-TB in the country.
    Scopus© Citations 1