Munkhkherlen, Erkhbilguun
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Товч нэр
Munkhkherlen, Erkhbilguun
Бүтэн нэр
Munkhkherlen Erkhbilguun
Латин нэр
Munkhkherlen Erkhbilguun
Албан тушаал
Судлаач
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Item type:Publication, Association of Salivary Mucin-7 Levels with Dental Caries in Adults(Mongolian National University of Medical Sciences, 2022-04-01); ; ; Objectives: This study examines the potential relationship between the incidence of dental caries in adults and the level of mucin-7 glycoprotein, a specific parameter in saliva. Methods: In a case-control study, samples of whole unstimulated saliva from 40 volunteers in two different groups were classified according to the decayed, missing, filled teeth (DMFT) index. One group was caries-free (n = 17), and the other had severe carries (n = 23). We measured the level of mucin-7, salivary buffer system, and pH and examined for relationships to the DMFT index. Results: There was a statistically significant difference among the groups (p < 0.001) in the level of mucin-7, salivary buffer system, and pH. The DMFT index for case and control groups was calculated as 0 and 14.09 ± 3.78. There was a strong, negative relationship between the level of mucin-7 and the DMFT index. Conclusion: The development of dental caries is linked to a reduced concentration of mucin-7 in saliva. The level of mucin-7 may be clinically useful for evaluating dental caries risk. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Measurement of atherosclerosis markers in individuals with periodontitis(XMLink, 2024-02); ; ; ; PURPOSE: The inflammatory response due to inflammatory cytokines, bacterial pathogens, and the altered lipoprotein metabolism in patients with periodontitis indicates that infection with periodontal anaerobic bacteria may influence atherogenesis in vitro and in vivo. We aimed to explore the effect of periodontitis concerning clinical and ultrasound markers of early atherosclerosis. METHODS: In this case-control study, a total of 30 systemically healthy adults (15 with periodontitis and 15 without periodontitis) over 40 years of age were studied. Periodontitis was determined by measuring the clinical attachment level (CAL) and radiographic bone loss (RBL). Conventional cardiovascular risk factors, including body mass index, serum levels of total cholesterol (TCH), triglycerides (TG), and high-density and low-density lipoprotein (HDL and LDL, respectively) cholesterol were evaluated. Carotid artery intima-media thickness (IMT) was measured using ultrasonography. RESULTS: The mean values of the CAL and carotid IMT were 5.02±0.9 mm and 0.084±0.01 cm vs. 1.6±0.61 mm and 0.072±0.02 cm in the periodontitis and healthy groups, respectively, reflecting statistically significant differences (P=0.001 and P=0.037, respectively). There were statistically significant differences in the serum levels of TCH, TG, and LDL between the 2 groups (P=0.017). The CAL and RBL were positively associated with carotid IMT and serum cholesterol levels, except for HDL, whereas tooth loss was not associated with any markers (P<0.05). Compared to the healthy group, participants with periodontitis exhibited 2.09 times higher odds (95% confidence interval, 1.22-3.59) of having subclinical atherosclerosis. CONCLUSIONS: The presence of periodontitis increased the risk of atherosclerosis.Scopus© Citations 4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Шүдний тулгуур эдийн үрэвсэлтэй хүмүүст судасны уян чанарт нөлөөлөх зарим хүчин зүйлийг тодорхойлсон дүн(2022-06-12); ; ;