Lkhagvasuren, Battuvshin
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Lkhagvasuren, Battuvshin
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Lkhagvasuren Battuvshin
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Lkhagvasuren Battuvshin
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Item type:Publication, Pancreas-Brain Crosstalk(2021); ;Mee-Inta, Onanong ;Zhao, Zi-Wei ;Hiramoto, TetsuyaThe neural regulation of glucose homeostasis in normal and challenged conditions involves the modulation of pancreatic islet-cell function. Compromising the pancreas innervation causes islet autoimmunity in type 1 diabetes and islet cell dysfunction in type 2 diabetes. However, despite the richly innervated nature of the pancreas, islet innervation remains ill-defined. Here, we review the neuroanatomical and humoral basis of the cross-talk between the endocrine pancreas and autonomic and sensory neurons. Identifying the neurocircuitry and neurochemistry of the neuro-insular network would provide clues to neuromodulation-based approaches for the prevention and treatment of diabetes and obesity.Scopus© Citations 33
