Sarantsetseg, Bandi
Loading...
Товч нэр
Sarantsetseg, Bandi
Бүтэн нэр
Sarantsetseg Bandi
Латин нэр
Sarantsetseg Bandi
Албан тушаал
Судлаач
3 results
Now showing 1 - 3 of 3
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, Effect of Antischemin Preparations on Platelet Hyperactivity in Diabetic Rabbit Model(Mongolian National University of Medical Sciences, 2021-04-01); ; ; Objectives: We aim to investigate how antischemin preparation affects the platelet parameters in a rabbit model with alloxan induced diabetes. Methods: Rabbits were divided into 4 groups; group 1 or control group, group 2 or no antischemin group without medication, group 3 or experimental group and group 4 or comparing group. Specific parameters such as PLT, PWD, MPV, P-LCR and PCT concentration were measured on day 3, 7, 14, 21 and 28. Results: Treatment of the no antischemin group with 6% alloxan monohydrate only resulted in a significant increase of platelet level and reached the highest value at 28th days (336.5 ± 21.2). When animals pre-treated simultaneously with antischemin for 5 days, the level of platelets did not increase significantly, compared to that in the non-treated group. After treatment of this group with 6% alloxan monohydrate, at the end of the trial (28 day), the platelet level was 274.7 ± 6.2 g/L, and in the clopidogrel pre-treated group, it was 274 ± 13.9 g/L. In the non-treated group, during the first 21 days, alloxan monohydrate caused a slight increase in PDW levels. Conclusions: Numerous studies revealed that botanical extracts which have been widely used as medicinal agents show potent anti-diabetic activity. Due to the serious side effects or resistance on synthetic drugs that are used in diabetes, the approach of using herbal remedies could be a successful alternative to the currently available diabetic treatments. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The hepatoprotective activity of the herbal preparation Salivin against carbon tetrachloride (Ccl4) induced hepatotoxicity in rabbits(De Gruyter Open, 2014-12-01); ; ; Abstract Recently, a trend has developed towards employing certain herbal medicines to manage hepatotoxicity. The present study is that of an assessment of the efficacy of a herbal preparation of Salivin (HPS), a combination of the herbs of Saussurea amara (L.)DC., Salsola collina Pall., Achillea asiatica Serg. and rhizomes of Glycyrrhiza uralensis Fisch, in rabbit models, against CCl4-induced hepatic damage. In so doing, an extract of HPS (200 mg/kg body weight/day), along with reference control tablets of Carsil (Silymarin 35 mg) (250 mg/kg body weight/day) (which is known for its hepatoprotective effects) were administered, along with the standard diet. The experimental group of rabbits received HPS orally for 28 days, which resulted in a decrease in blood enzymes (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase), compared to the control. Evidenced by biochemical and histopathological studies, it is concluded that the polyherbal formulation HPS showed hepatoprotective activity against induced CCl4 hepatotoxicity in rabbits. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Effect of Antischemin Preparations on Hypoxia(Mongolian National University of Medical Sciences, 2021-04-01); ; ; Objectives: We have aimed to determine the anti-hypoxic action of antischemin, an active anti-inflammatory drug that protects brain cells from damage and death during cerebral hemorrhage and hypoxia. Methods: We have studied antischemin made from Astragalus membraneceus roots, Scutellaria baicalensis Georgi roots, and Gingko Biloba leaves denizen in Mongolia and compared its protective effect against hypoxia compared to each of its constituents alone 6 groups of 8 mice. Normobaric hypoxia resistance as well as tissue hypoxia resistance was determined. Results: For antischemin preparation 100 mg/kg, the tolerance of normobaric hypoxia was 42 minutes or 47.2% higher in the treatment group (p < 0.001), and the latent period of hypoxia was increased by 22.7% (p < 0.05). The period of hypoxia increased 32% (p < 0.001). Conclusions: Antischemin has been shown to make tissue more resistant to hypoxia and and have more anti-hypoxic activity than its constituents alone.