Banzar, Mungun
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Товч нэр
Banzar, Mungun
Бүтэн нэр
Banzar Mungun
Латин нэр
Banzar Mungun
Албан тушаал
Судлаач
ORCID
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Item type:Publication, Invasive Hemodynamic Monitoring and Arterial Blood Gas Exchange During Spinal vs General Anesthesia for Cesarean Delivery in Mongolian Parturient(Mongolian National University of Medical Sciences, 2024-12-12); ; ; Objective: This study investigated the accuracy and precision of continuous, invasive blood pressure obtained using the arterial line system in patients undergoing cesarean section with spinal and general anesthesia. Methods: A total of 150 parturient women who underwent C-sections from July 1, 2021, to Dec 30, 2023, were divided into two groups: the GA (general anesthesia) group (n=50) and the SA (spinal anesthesia) group (n=100). In this prospective observational study, we measured and compared the changes in hemodynamic fluctuation and arterial blood gas deviations under C-section with either spinal or general anesthesia. Results: One hundred fifty patients were recruited for the study after exclusions, and data were analyzed for 150 patients. There were no significant differences in the time from anesthesia to incision, the operation duration, infused crystalloid volume, blood loss, and urine output. The most frequent complications were surgery hypotension, tachycardia, nausea, and headache in the SA group, and tachycardia, hypertension, in the GA group These complications may cause SA’s impact on the sympathetic nerves, resulting in dilated blood vessels and reflex tachycardia. Conclusion: It has been suggested that the choice of anesthesia technique has a significant impact on hemodynamic stability during cesarean section. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, A Comparative Study of Brain Injury Biomarker S100β During General and Spinal Anesthesia for Caesarean Delivery: A Prospective Study(MDPI AG, 2025-07); ; ; Background and Objectives: Anesthetic agents may influence brain function, and emerging evidence suggests possible neurotoxicity under certain conditions. S100β is a well-established biomarker of brain injury and blood-brain barrier disruption, and its prolonged elevation beyond 6-12 h, despite a short half-life, may indicate ongoing neuronal injury. Its use in cesarean section (C-section) remains limited, despite the potential neurological implications of both surgical stress and anesthetic technique. This study evaluates potential brain injury during caesarean section by comparing maternal and neonatal S100β levels under general and spinal anesthesia. Materials and Methods: This observational prospective study compared changes in the S100β brain damage biomarker in maternal (pre- and post-surgery) and umbilical artery blood during elective c-sections under general or spinal anesthesia. The 60 parturient women who underwent a C-section from 1 July 2021 to 30 December 2023 were evenly distributed into 2 groups: General anesthesia (GA) (n = 30) and Spinal anesthesia (SA) group (n = 30). It included healthy term pregnant women aged 18-40, ASA I-II and excluded those with major comorbidities or emergency conditions. Results: S100β concentrations slightly increased once the C-section was over in both the SA and GA groups, but without notable differences. In the SA and GA groups, preoperative S100β concentration in maternal blood was 195.1 ± 36.2 ng/L, 193.0 ± 54.3 ng/L, then increased to 200.9 ± 42.9 ng/L, 197.0 ± 42.7 at the end of operation. There was no statistically significant difference in S100β concentrations between the spinal and general anesthesia groups (p = 0.86). Conclusions: S100β concentrations slightly increased after C-section in both groups. The form of anesthesia seems to be irrelevant for the S100β level. However, further research is needed to confirm these findings and fully evaluate any potential long-term effects.