Dondov, Ganchimeg
Loading...
Товч нэр
Dondov, Ganchimeg
Бүтэн нэр
Dondov Ganchimeg
Латин нэр
Dondov Ganchimeg
Албан тушаал
Судлаач
ORCID
Scopus Author ID
8 results
Now showing 1 - 8 of 8
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, Incidence of Stomach and Esophageal Cancers in Mongolia: Data from 2009 to 2018.(2020); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The Dynamics of the Prevalence of Acute Viral Hepatitis and the Strategies against Viral Hepatitis in Mongolia(2024); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Determining Gastric Cancer-Related Risk Factors in Mongolian Population Using ABC(D) Method: A Matched Case-Control Study.(2022-03); ; Scopus© Citations 5 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Genetic Risk of MASLD in Mongolians: Role of PNPLA3 and FTO SNPs(2025-08); Dashjamts, GantogtokhBACKGROUND: This study aimed to determine the association between PNPLA3 rs738409, rs2896019, and FTO rs9939609, rs17817449 single-nucleotide polymorphisms and the risk of metabolic dysfunction-associated steatotic liver disease (MASLD) in Mongolian individuals. METHODS: We conducted a case-control study, enrolling 100 MASLD patients and 50 subjects without MASLD. We used the PCR-RFLP technique on three genotype SNPs (rs738409, rs2896019 in PNPLA3, and rs9939609 in FTO). We analyzed liver function and lipid metabolism parameters in the peripheral blood of study participants. A p-value below 0.05 was considered a statistically significant result. RESULTS: This study, which included 150 participants aged 23 to 75, had a mean age of 46.73 ± 11.45 years, with 40% of participants being male (60 individuals). We observed the rs738409 (G), rs2896019 (G), and rs9939609 (A) alleles at a statistically significantly enhanced frequency in the case group (32.5%, 33%, and 21%) compared to the control group (19%, 25%, and 19%), indicating an increased risk of MASLD. The FTO rs17817449 SNP did not show a significant difference between groups. PNPLA3 rs738409 GC/GG genotype (OR = 2.39, p = 0.019) and FTO rs9939609 AT/AA (OR = 2.55, p = 0.025) genotype showed a significant association with MASLD. In the evaluation of the FTO rs9939609, rs17817449, and PNPLA3 rs738409, rs2896019 single-nucleotide polymorphisms among the research individuals, 18.7% had no SNPs, 15.3% had one SNP, 29.3% had two SNPs, 25.3% had three SNPs, and 11.3% had four SNPs. The risk of MASLD increased significantly for individuals having four SNPs (OR = 4.23, p = 0.007). CONCLUSIONS: We found that PNPLA3 rs738409 GC/GG genotype and FTO rs9939609 AT/AA genotype are strongly associated with an increased risk of MASLD. Notably, individuals with a higher rate of SNP number, had a significantly higher risk of MASLD.Scopus© Citations 6 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Renal Function in Chronic Hepatitis C Patients in Mongolia.(2025-06) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Change in Estimated Glomerular Filtration Rate After Direct-Acting Antiviral Treatment in Chronic Hepatitis C Patients.(2025-01)Scopus© Citations 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Post-Treatment Occurrence of Serum Cryoglobulinemia in Chronic Hepatitis C Patients.(2024-06); Nergui, OtgongerelScopus© Citations 3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Diagnostic performances of pepsinogens and gastrin-17 for atrophic gastritis and gastric cancer in Mongolian subjects(2022); Scopus© Citations 15