Tsedenbal, Batchimeg

Now showing 1 - 2 of 2

Some of the metrics are blocked by your
consent settings
Relationship between Uterine Cervical Cytopathology and Histopathology in Mongolia
(Mongolian National University of Medical Sciences, 2020-04-01)
Uyanga Gotov
;
Batchimeg Tsedenbal
;
Enkhtuya Sharkhuu
;
Dondov Oyunchimeg
;
Bayarmaa Enkhbat
Objectives: This study aimed to evaluate the correlation between uterine cervical squamous cell abnormalities by conventional cytology and corresponding histopathology, and to assess the accuracy between them. Methods: A total of 192 cytological smears of patients with squamous cell abnormalities who underwent colposcopy examination from April – December 2015 were included in this study. The final agreement between cytology and histopathology was defined by the evaluation of histology as a golden standard. Results: The agreement between cytology and histopathology evaluation was 65.6%, and the discrepancy was 33.6% (k=0.512). When the classes of cytology were evaluated for accuracy, it was discovered that NILM* had a higher sensitivity of 77.0%, a specificity of 87.0%, a false positive of 23% and a false negative of 13.0% (k=0.711). Among the LSIL cases a sensitivity was discovered of 39.0%, a specificity of 82.7%, a false positive of 61.0% and a false negative of 17.3% (k=0.392. However, in HSIL sensitivity dropped to 37.8%, specificity increased to 91.6%, false positive were 62.0% and false negative were 8.4% (k=0.501). Conclusion: The agreement for diagnosis of uterine cervical cytology and histopathology was 65.6% (n = 126) and the discrepancy was 33.6% (n = 64) (p = 0.001). The correlation between cervical cytology and histopathology remained moderate (kappa=0.512). Thus, it is proposed that an appropriate quality control system for the cytopathological confirmation may contribute to the further detection and treatment for uterine cervical cancer in Mongolia.
Some of the metrics are blocked by your
consent settings
Human papillomavirus genotyping among women with cervical abnormalities in Ulaanbaatar, Mongolia
(Elsevier BV, 2018-12)
Tsedenbal, Batchimeg
;
Yoshida, Tomomi
;
Enkhbat, Bayarmaa
;
Gotov, Uyanga
;
Sharkhuu, Enkhtuya
OBJECTIVES: Few studies on human papillomavirus (HPV) have been conducted in Mongolia. This study was performed to evaluate the prevalent HPV genotypes and their associations with cytology and demographic and behavioral characteristics in Mongolian women with cervical abnormalities. METHODS: Exfoliated cell samples of 100 women who had a previous history of cervical abnormality were collected. Cytological interpretation was conducted microscopically and HPV genotyping was performed using the Roche Linear Array test. Study questionnaires were completed. RESULTS: Overall, 25 HPV genotypes were detected in 47% of participants, and the most prevalent were HPV 16, 52, 58, and 33. Cytological examination revealed 12% of participants had atypical squamous cells of undetermined significance (ASC-US), 8% had low-grade squamous intraepithelial lesions (LSIL), 7% had high-grade squamous intraepithelial lesions (HSIL), and 14% had squamous cell carcinoma (SCC), while 59% of women had a normal cytology. HPV 16 was the most common type among women with a normal cytology and cervical cancer. However, women with cervical abnormalities including LSIL and HSIL were predominantly infected with HPV 52. Moreover, women aged <35 years had a significantly higher risk of HPV infection than those in the other age groups (p<0.05). CONCLUSIONS: The prevalent trend of HPV genotypes observed in this cohort differs from that reported previously in Mongolia. These data may contribute to developing an effective strategy for cervical cancer prevention in Mongolia.
Scopus© Citations 11

Tsedenbal, Batchimeg

Filters

Settings

Sort By

Results per page