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    The hepatoprotective activity of the herbal preparation Salivin against carbon tetrachloride (Ccl4) induced hepatotoxicity in rabbits
    (De Gruyter Open, 2014-12-01) ; ;
    Batgerel Luvsansharav
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    Abstract Recently, a trend has developed towards employing certain herbal medicines to manage hepatotoxicity. The present study is that of an assessment of the efficacy of a herbal preparation of Salivin (HPS), a combination of the herbs of Saussurea amara (L.)DC., Salsola collina Pall., Achillea asiatica Serg. and rhizomes of Glycyrrhiza uralensis Fisch, in rabbit models, against CCl4-induced hepatic damage. In so doing, an extract of HPS (200 mg/kg body weight/day), along with reference control tablets of Carsil (Silymarin 35 mg) (250 mg/kg body weight/day) (which is known for its hepatoprotective effects) were administered, along with the standard diet. The experimental group of rabbits received HPS orally for 28 days, which resulted in a decrease in blood enzymes (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase), compared to the control. Evidenced by biochemical and histopathological studies, it is concluded that the polyherbal formulation HPS showed hepatoprotective activity against induced CCl4 hepatotoxicity in rabbits.
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    Effect of “Antischemin” Upon Lipid Peroxidation Process on Brain Ischemic Disorder Induced on Experimental Rat Model
    In recent years, wide range drug development research that prevents cerebral tissue and cell necrosis, degradation are being carried out. The purpose of our research is to determine effect of “Antischemin” during stimulation of lipid peroxidation on white rat brain ischemic disorder model. We have performed using Farkes E et al 2007 methodology. Our study of brain ischemia induced model in experimental white rat shows that Antischemin inhibits lipid peroxidation and has neuro-protective effects from neuron necrosis, degradation.
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    Relationship Between Some Parameters of the Membrane-Redox Potentials Three-State Line System with the Human Constitutional Types of Traditional Medicine
    (Mongolian National University of Medical Sciences, 2015-09-25) ; ; ;
    Objectives: According to Tibetan-Mongolian traditional medicine theory, humans are classified into three main individuals based on the Rlung, Mkhris or Badgan symbolic code (SC). Our objective was to research the relationship between some parameters of membrane-redox potentials three-state line system in relation to the human constitutions of traditional medicine. Methods: The quantities ratio for the SC of Rlung, Mkhris, and Badgan was determined by the Doc-Am-I program. We determined the lipid profile, erythrocyte membrane resistance capacity and body mass index. Results: It was shown that the concentration of serum lipids, body mass index and membrane resistance capacity of individuals of the Badgan SC group was increased with statistical significance in comparison to the other two groups. Our study revealed that people of Rlung SC group were characterized by the highest concentration of malondialdehyde and the lowest rate of membrane resistance capacity compared to people of the other two SC groups. Conclusion: Our study defined the relevance of the membrane redox potentials three-state line system in connection to the human constitutional types such as the abstractly coded classifications of Rlung, Mkhris, and Badgan of traditional medicine.