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Electrocardiographic and echocardiographic findings in long COVID-19: analyzing repolarization alterations and cardiac abnormalities
Зохиогч
Он
2024 оны арван хоёрдугаар сарын 17
Төрөл
journal article
Journal
Kreativnaya kardiologiya
Volume
18
Issue
S
ISSN
1997-3187
2410-9169
Хураангуй
Purpose.This study aims to identify and compare ECG and echocardiographic abnormalities in long COVID-19 patients, highlighting potential cardiac indicators. Material and methods.A hospital-based cross-sectional study with case-control analysis was conducted, we will add a detailed explanation of how patients were categorized into case (n = 60) and control groups (n = 60), based on specific criteria such as previously COVID-19 test, symptoms, ECG and echocardiographics with long COVID-19 related changes.Cardiac repolarization parameters, including TpTe interval and QTc interval, were evaluated through electrocardiography (ECG) (Nihon Kohden, 2016).Additionally, echocardiography (Xario 200, Canon, 2018) was employed to assess reactive pericarditis, cardiac contractility, and relaxation.Laboratory data were collected, and statistical analysis was performed using SPSS 26.0 software. Results.The study cohort had an average age of 45.7 ± 13.4 years.Among the findings, 35.7% of patients exhibited increased pericardial echogenicity, 23% had suspected reactive pericarditis, while 35.7% showed no elevated pericardial echogenicity.The Tp/Te interval, indicative of cardiac repolarization, was significantly prolonged in the case group (0.139 ± 0.02 sec) compared to the control group (0.089 ± 0.01 sec) (p < 0.001).Similarly, the QTc interval was extended by 0.559 ± 0.08 sec in the case group (QTc interval prolongation > 0.480 sec), demonstrating a significant difference from the control group (0.421 ± 0.03 sec) (p < 0.001).The linear regression analysis revealed significant associations between repolarization changes and several predictors in long COVID-19 patients.Notably, elevated triglycerides (β = 0.17, p < 0.001), cholesterol levels (β = 0.11, p < 0.001), TpTe (β = 2.09, p < 0.001), and reactive pericarditis (β = 0.05, p < 0.05) were identified as significant predictors of long COVID-19.Conclusion.Reactive pericarditis and repolarization changes, including TpTe and pericardial layer parameters, may manifest during the course of long COVID-19.