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Jaalkhorol, Myadagmaa

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Товч нэр
Jaalkhorol, Myadagmaa
Бүтэн нэр
Jaalkhorol Myadagmaa
Латин нэр
Jaalkhorol Myadagmaa
Албан тушаал
Судлаач
Харьяалал
ORCID

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    Multiple Sclerosis in Mongolia; the First Study Exploring Predictors of Disability and Depression in Mongolian MS Patients
    (MDPI AG, 2023-01)
    Jaalkhorol, Myadagmaa
    ;
    Dulamsuren, Oyunbileg
    ;
    Dashtseren, Amarsaikhan
    ;
    Byambajav, Enkh-Amgalan
    ;
    Khaidav, Nansalmaa
    Mongolia is located at 45° north latitude in the center of the Asian continent, and about 80% of the territory is at 1000 m above sea level. Epidemiologically, multiple sclerosis (MS) has not been investigated in Mongolia, although there have been a few MS case reports. We investigated the characteristics of MS in Mongolia for the first time, focusing on the association between MS-related parameters and depression levels. We initiated cross-sectional analyses, using data from 27 MS patients aged 20 to 60 years in Ulaanbaatar, Mongolia. The patients completed a questionnaire on their lifestyles and clinical information. We classified the MS patients on the basis of disability levels using the expanded disability status scale (EDSS) scores: 11.1% mild disability and 88.9% moderate to severe disability (median EDSS score, 5.5). We also classified the patients on the basis of depression levels using the 9-item patient health questionnaire (PHQ-9) scores: 44.4% mild depression, 40.7% moderate depression, and 14.8% severe depression (mean PHQ-9's score, 9.96 ± 5.05). We used multivariate logistical regression analyses to identify predictors of EDSS or PHQ-9 scores. Disability levels were associated with vision and balance problems. Depression levels were associated with corticosteroid treatment; no patients were treated with disease-modifying drugs (DMDs). The odds ratios for disease onset age and treatment duration were associated with EDSS scores. In conclusion, MS onset age and treatment duration were independent predicting factors influencing the level of disability. Appropriate DMD treatment would lower the disability and depression levels.
    Scopus© Citations 4
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    Is 2D:4D digit ratio related to avowed religion? A study among Mongolian young males from Ulaanbaatar
    (Wiley, 2023-11)
    Jaalkhorol, Myadagmaa
    ;
    Bat-Orgil, Badrangui
    ;
    Lkhagvasuren, Khorolsuren
    ;
    Dashtseren, Amarsaikhan
    ;
    Dulamsuren, Oyunbileg
    BACKGROUND: The ratio of the second- (2D) to fourth (4D) digit lengths of hand (2D:4D) is a proxy marker of the relative testosterone and estrogen concentration during a relatively narrow period of fetal development that might affect behavioral and personality characteristics. AIM: To estimate the differences in 2D:4D between different religious groups among a sample of young adult males in Mongolia. METHODS: Two hundred and sixty-five Mongolian male students with mean age of 20.5 (SD = 1.7) years from different universities in Ulan Bator, were included in the study. Information on age, religious affiliation, marital status and parental education were obtained directly from each study participant. Digit lengths were measured from scanned images by using the ImageJ software 1.53 K. One-way analysis of variance was employed to evaluate whether they were significant differences in 2D:4D ratio between groups, along with Scheffe's post hoc comparison. RESULTS: Study participants significantly differed in 2D:4D across religion. Left 2D:4D, but not the right, showed a significant difference between religions, with Muslims exhibiting the highest 2D:4D mean and the lowest DR-L . CONCLUSION: Our study suggests that the 2D:4D ratio is related to the participants' religion. However, the distinctiveness of the Muslim students from study participants belonging to other religious groups in this study could also be related to ethnic differences, given that the students were Kazakhs. This is, to our knowledge, the only study looking at the relationship between the 2D:4D ratio and religious affiliation and, thus, further research is needed to confirm its results.
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    Factors associated with vitamin D levels in Mongolian patients with multiple sclerosis
    (Public Library of Science (PLoS), 2025)
    Jaalkhorol, Myadagmaa
    ;
    Dashtseren, Amarsaikhan
    ;
    Magnaibayar, Gantuya
    ;
    Bat-Orgil, Badrangui
    ;
    Tsunoda, Ikuo
    BACKGROUND: Multiple sclerosis (MS) onset is caused by genetic and environmental factors. Vitamin D has been identified as contributing environmental risk factor, with higher prevalence at latitudes further from the equator. Mongolia, at 45°N, has limited sunlight exposure, increasing the population's risk for vitamin D deficiency. OBJECTIVES: To compare vitamin D levels between persons with MS (pwMS) and persons without MS and to identify factors associated with low vitamin D. METHODS: We investigated associations with vitamin D levels using data from MS cases and controls from Mongolia. We used linear mixed-effects regression with fixed effects (case status, sociodemographics, and predefined variables) and participant-specific random intercepts. RESULTS: Of 62 participants (31 pwMS, 31 controls), pwMS had lower summer [median 23.00 ng/ml (interquartile range 11.30-31.50) vs. 25.00 ng/ml (19.25-32.00)] and winter vitamin D levels [21.00 ng/ml (10.60-27.60) vs. 23.50 ng/ml (15.55-28.60)], with a smaller seasonal decline. Vitamin D deficiency was more prevalent in pwMS. None of these findings reached statistical significance. Winter season and being breastfed as a child were associated with significantly lower vitamin D levels. CONCLUSION: Vitamin D deficiency was common among pwMS, which could be influenced by behavioural factors. These findings may inform more targeted recommendations for pwMS to maintain sufficient vitamin D levels.