Dorjkhuu, Amgalanbaatar
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Товч нэр
Dorjkhuu, Amgalanbaatar
Бүтэн нэр
Dorjkhuu Amgalanbaatar
Латин нэр
Dorjkhuu Amgalanbaatar
Албан тушаал
Судлаач
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15 results
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Item type:Publication, A study on structure and functions of organs involved in the formation of Mongolian Khuumii sound(Mongolian Journals Online, 2020-10-27); ; ; Palamdorj, Ganchimeg - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Efficacy of Marmot Brown Fat in Treatment of Acute Pancreatitis(Mongolian National University of Medical Sciences, 2016-06-25); ; ; Ariunaa ZunduinObjectives: The brown fat of marmots is called "human meat" among Mongolian people because they abstain from eating it. Our experimental study is the first academic-based study to investigate the effect of marmot brown fat (MBF) on acute pancreatitis (AP). Methods: This study used 82 healthy female Wistar rats (250-280 g). The study rats were divided into 4 groups: (1) relatively healthy (no medication and no AP, n = 10), (2) caerulein-induced AP rats without any treatments (n = 24), (3) AP rats fed by the MBF suspension (n = 24), and (4) AP rats injected with sandostatin (n = 24). The serum a-amylase level (SAAL) and histological examination were observed. Results: Significantly increased SAAL (group 1: 1347.10 ±10.76 units/L vs group 2: 1804.50 ±134.32 units/L) was confirmed in rats with caerulein-induced, mild AP. In both treatment groups 3 and 4, the SAAL was significantly decreased on the fifth day after treatment. Interestingly, advanced damage of pancreatic cells was observed in group 3. Additionally, the health condition of group 3 rats was poor, and spleen and lung tissue damage was detected by histological examination. Conclusion: Our study results suggest that the MBF suspension might be stimulating pancreatic juice secretion, therefore we conclude that the MBF suspension is not beneficial in the treatment of AP. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The Structure of The Choroid Plexus of Adult and Children Brain Ventricles(Elsevier BV, 2015-10-20); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Structural Changes in Vertebrae of Mice Based on Experimental Model of Rheumatoid Arthritis(Scientific Research Publishing, 2018-01-01); Studies have shown that autoimmunity causes pathogenesis of more than 100 diseases. Among these diseases, approximately 1-2% of the world’s population has rheumatoid arthritis disease, which is a chronic disease that affects 45 out of every 3000 people who have autoimmune diseases. The aim of this research is to address the possible treatment of rheumatoid arthritis disease by comparing and contrasting the effectiveness and influence that treatments have on treating the disease. This study will be conducted by inducing the following treatments: ibuprofen and Boigor-10 on model animal subjects (mice) to determine the outcomes of the treatment. We will assess the outcomes by investigate the structural changes on vertebrae and joints of these subjects and the clinical manifestation score of each treatment. We hypothesize that these treatments will improve the treatment of rheumatoid arthritis disease. Furthermore, we hope that this research contributes to further understanding autoimmune disease and promotes proper treatment of the disease. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Comparative Study on Macroscopic Anatomy of Human Placenta in Term and Post Term Pregnancy(Mongolian National University of Medical Sciences, 2020-09-25); ; ; ; Objectives: We aimed to compare the macroscopic anatomy of human placenta in term and post-term pregnancy. Methods: This maternity hospital-based comparative study was carried out in Mongolia, in the year 2017-2018. For study purposes, placentae were collected from 1061 women between 17-44 years of age with live birth only. Term: 38 weeks to 40 weeks gestational period, and post-term: beyond 41 weeks gestational period. The macroscopic features of the placentae were measured as a standard protocol that is approved Department of Anatomy, Mongolian National University of Medical Sciences. Results: A total of rounded shapes was found in 72% of cases and oval in 26.3% cases, irregular shape in 1.7% cases of the three shape groups. The width and the weight of the placenta (t = 7.20, t = 13.27 respectively) were compared between groups term and post-term found to be significant (p < 0.001). Conclusions: We conclude that irrespective of term or post-term placentae, most of the placentae were round in shape. The averages of placental morphometric parameters of both of term or post-term placentae are in the normal limit. This study concludes that as the gestational period increases length, width, thickness, and weight of placenta increases in different. - Some of the metrics are blocked by yourconsent settings
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Item type:Publication, Preliminary Study Results of Native Mongolian Inonotus Obliquus Extracts in Alloxan-Induced Diabetic Rats(Mongolian National University of Medical Sciences, 2020-12-29); ; ; Objectives: We aimed to investigate the morphological changes and clinical chemistry panel of alloxan-induced diabetic rats for the treatment groups of ethanol or aqueous extracts of Mongolian natural Inonotus obliquus. Methods: Wistar albino rats (n = 80) were randomly assigned into four groups: 1. Healthy control group, 2. Untreated diabetic group, 3. Diabetic group treated with Inonotus obliquus (500 mg/kg per day) water extract, 4. Diabetic group with Inonotus obliquus (500 mg/kg per day) ethanol extract. Diabetes was induced by alloxan 150 mg/kg (single intraperitoneal injection) in the diabetic groups. Results: Both water and ethanol extract of Inonotus obliquus reduced the blood glucose level of diabetes at 48 h after treatment. Histologic and morphology examinations showed that water extracts of Inonotus obliquus alleviated the damage to pancreas tissues in alloxan diabetic rats. Conclusions: We postulate that simple ethanol and water extracts of natural Mongolian Inonotus obliquus have an antihyperglycemic effect that enhances islet cell function in alloxan-induced diabetic rats. The extracts of Mongolian natural Inonotus obliquus are easily producible at low cost and should be further explored as a treatment for diabetes. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Илүү тээлтийн үед ихсэд гарах бичил бүтцийн өөрчлөлт(2020-02-15); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Хэвийн болон илүү тээлтийн үеийн хүйн бүтэц(2021-04-06); Үндэслэл: Жирэмсний илүү тээлт нь төрөх хүчний гажуудал үүсгэдэг, перинаталь эндэгдэл, төрсний дараа цус алдалтыг нэмэгдүүлдэг эх барихын практикт анхаарал татахуйц асуудлын нэг болдог байна. Манай судлаачдын тооцоолсоноор нийт төрөлтийн 6 хувийг илүү тээлт эзэлж байна. Зорилго: Хэвийн болон илүү тээлттэй төрсөн эхийн хүйн урт, бэхлэгдсэн байдал, бичил бүтцийг харьцуулан судлах. Хэрэглэгдэхүүн: Нийслэлийн Өргөө, Хүрээ, Амгалан амаржих газар, ЭХЭМҮТ-д 20172018 онд үйлчлүүлсэн хэвийн 381-6-401-6 болон 41 долоо хоногоос дээш илүү тээлттэй төрсөн 1061 эхчүүдийн хүйг авч ашигласан. Арга зүй: Хүй бэхлэгдсэн байдлыг төвд, захад, дунд, хальсан дээр 4 хэлбэрээр тодорхойллоо. Хүйн бичил бүтцийг Гематоксилин эозин болон Трихром Массон ВанГинзон будгийг хэрэглэн тодорхойлов. Үр дүн: Судалгаанд хамрагдсан хэвийн тээлттэй эхийн 695 хүйн уртын хэмжээ 27.00-90.00 см-ийн хооронд хэлбэлзэж дундаж нь 56.47±0.334 см байсан бөгөөд илүү тээлттэй 366 хүйн уртын хэмжээ 33.00-92.00 см-ийн хооронд хэлбэлзэж дундаж нь 57.667±0.456 см байлаа, p<0.05. Хүй бэхлэгдсэн байдал нь статистик бодит ялгаагүй байна. Хэвийн тээлтийн үед хөндлөн зүслэг дээр хүйний артерийн эндотелийн эсүүд нь суурийн мембран дээр байрлахдаа олон эгнээ үүсгэн байршиж түүний бөөмүүд нь дээр доор сөөлжиж харагдаж байна. Илүү тээлтийн үед хүйн артерийн хананы нэг тал голомтлог байдлаар холбогч эдийн ширхэгүүд олширч зузаарч, булчинлаг давхаргад гөлгөр булчингийн ширхэгүүд үелсэн бүтэц үүсгэсэн нь ажиглагдаж байна. Хэвийн тээлтийн үед венийн судасны хөндлөн огтлолд суурийн мембран дээр зэрэгцэн суусан хавтгай эндотелийн эсүүд түүний доор орших нимгэн эндотелийн доод давхарга ажиглагдаж байна. Илүү тээлтийн үед венийн судасны булчинлаг бүрхүүл сийрэгжсэн, хөвсийж хавагнан холбогч эдийн давхаргуудад хоосовч зайнууд үүссэн байна. Дүгнэлт: Хэвийн болон илүү тээлттэй хүйн урт, бичил бүтэц бодит ялгаатай, хүй бэхлэгдсэн байдал бодит ялгаагүй байна. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Илүү болон хэвийн тээлтийн үед ихсийн сорьцонд уургийн идэвхжилийг үнэлсэн дүн(2020-05-01); ; Introduction: Post-term pregnancy is one the major issues in obstetric practice, which can lead to birth complications and increase perinatal mortality and postpartum hemorrhage. One of the urgent obstetric problems in Mongolia is the management of early detection of 41-week -old pregnant women and the management of childbirth, which is why our work with scaring of placenta and morphometric parameters at extrauterine births, including protein activation, is extremely rare. Purpose: Determination of SHP2 and P-P38 protein activation in placenta specimens at higher and normal premature exposures. Materials and methods: Immunoblotting methods were widely used to determine the expression of any protein. Protein concentrations from placental tissue of normal-term and more post-term mothers were determined using an ELISA reader in BCA (Bicinchonic acid assay) test album. Diluted 2μl of the protein suspension and diluted with 23μl of PBS (Phosphate Buffer solution) and added 200μL of the BCA (Bicinchonic acid assay) working solution. Results: Asa result SHP2 protein synthesis was significantly increased in the control placenta or normal-term placenta sample of our study. Our result showed that SHP2 protein activity was low in plots 1 and 2 plots, whereas SHP2 protein activity was high in samples 3 and 4 plots. However, in the case group or during post-term delivery, SHP2 protein synthesis was high in the total placenta specimen. During normal-term and post-term delivery excess openings, the activation of phosphorylated p38 protein, a transcription factor for inflammation was not identified in the placenta specimen. Conclusion: At post-term delivery SHP2 protein synthesis was significantly higher in placenta specimens than in normal-term delivery open plots.