Lkhagvasuren, Nasantsengel
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Товч нэр
Lkhagvasuren, Nasantsengel
Бүтэн нэр
Lkhagvasuren Nasantsengel
Латин нэр
Lkhagvasuren Nasantsengel
Албан тушаал
Судлаач
11 results
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Item type:Publication, Changes in mental health following COVID-19 infection: Results of a prospective cohort study in Mongolia(Mongolian National University of Medical Sciences, 2026-03-30); ; Yelik MadiObjective: COVID-19 has been associated with persistent neuropsychiatric complications, yet prospective evidence from low- and middle-income countries remains limited. This study evaluated 12-month longitudinal changes in depression, anxiety, insomnia, and post-traumatic stress disorder (PTSD) among hospitalized patients with COVID-19 compared with non-COVID-19 controls in Mongolia. Methods: This prospective cohort study included 459 adults (326 COVID-19 cases and 133 controls) recruited from hospitals affiliated with the Mongolian National University of Medical Sciences between 2021 and 2023. Participants without baseline mental disorders were assessed at 7–14 days, 3 months, and 12 months using the PHQ-9, GAD-7, ISI, and PCL-5. Data were analyzed using X² tests, independent t-tests, and relative risk (RR) estimates, with statistical significance defined as p < 0.05. Results: The mean age of participants was 46.3 ± 13.8 years, and 58.4% were female. At 12 months, depression (37.3% vs. 16.9%; RR = 2.22, 95% CI: 1.28–3.83; p = 0.003) and anxiety (28.0% vs. 11.2%; RR = 2.49, 95% CI: 1.25–4.96; p = 0.006) remained significantly more common in the COVID-19 group than in controls. Insomnia decreased over time (33.3% vs. 49.4%; RR = 0.67; p = 0.037), whereas PTSD prevalence remained low in both groups (<3%, p > 0.05). Female participants and those aged 40–59 years showed a higher risk of adverse mental health outcomes. Conclusions: COVID-19 infection was associated with a significantly increased long-term risk of depression and anxiety up to 12 months after infection. These findings support routine mental health screening and sustained psychological follow-up as part of post-COVID care and provide evidence to inform long-term mental health policy in Mongolia. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Lead Hair Level Impact on Mongolian Children with Attention Deficit Hyperactivity Disorder(Scientific Research Publishing, 2020-01-01); ; ; ; Background: High-prevalence disorders among children are attention-deficit/ hyperactivity disorder (ADHD) and lead exposure. The purpose of this study was to find out the relationship between ADHD symptoms and hair lead levels and neurocognitive function among Mongolian children. Methods: This was the case study to investigate the relationship between hair lead and ADHD in Mongolian school kids. We conducted a pair-matching case-control study with 30 ADHD cases and 30 non ADHD controls for 7 - 12 years of age school children, based on the same age, and sex. Recruitment process was conducted from June 2018 to December 2019. The case and control study children were systematically selected by structured diagnostic interviews, including caregiver interviews based on the Diagnostic and Statistical Manual of Mental Disorders, 4th ed (DSM-IV). Results: The average level of hair lead of the ADHD group was 1.45 ± 2.93 ppm and the control group’s lead level was 0.7 ± 1.59 ppm. We found ADHD-Combined (ADHD-C) patients showed the highest lead levels (p −0.329 and −0.242, for original and log10 transformed, p < 0.001). The lead was linked with vulnerability to ADHD and symptom severity among those school-age children. Conclusions: The child hair lead exposure is one of the risk factors of the development of ADHD and decreasing FSIQ (Full Scale Intelligent Quotient) and EQ level of children and linked with susceptibility to ADHD and symptom severity in school-age children. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Жирэмсэн үеийн сэтгэл гутралын тархалт түүнд нөлөөлөх зарим эрсдэлт хүчин зүйлсийг судалсан байдал(2023-11-03) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Мансууруулах бодистой холбоотой гэмт хэрэгт холбогдогчдын сэтгэцийн эрүүл мэндийн зарим асуудал(2021-03-13) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Ковид-19-ийн дараах сэтгэцийн эрүүл мэндийн өөрчлөлт: проспектив когорт судалгааны үр дүн(2025-12-05); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Говь-Алтай аймгийн өсвөр үеийнхний сэтгэл хөдлөл, зан үйлийн илэрлийг судалсан нь(2021-09-01); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Synergistic SNP-SNP interaction of NRG1 and ERBB4 increases the risk of schizophrenia(2025-09); ; In last two decades, quite of few evidences were found about the genetic risk factor for schizophrenia. But until now, it's poorly understood that the pathogenesis of schizophrenia and contribution of those genetic factors in it. Inconsistent data reported for several candidate gene polymorphisms contributing on schizophrenia development, previously. The case-control study was conducted with 102 schizophrenia patients and 150 control subjects. HTR2A (rs6311), TPH2 (rs1386494), NRG1 (rs3924999 and rs2954041), DISC1 (rs821616 and rs6675281) and ERBB4 (rs7424835 and rs4673628) gene polymorphisms were detected by allele specific PCR and RFLP. Genetic analysis were performed by SNPAlyze 9.0 and STATA 13.0 software. Also, multidimensional regression analysis was used to determine the SNP-SNP interaction. T allele of rs821616 DISC1 and G allele of rs4673628 ERBB4, were associated with increased risk of schizophrenia. Significant difference was observed for heterozygous G/A genotype of rs6311 (G/A vs G/G + A/A, OR = 2.11; 95 % CI, 1.25-3.54, p = 0.005). By SNP-SNP interaction, the cumulative effect of NRG1 (rs3924999) and ERBB4 (rs4673628) combination, had increasing the risk of schizophrenia by 9.44-fold. This data require independent replication for rs821616, rs4673628 and rs6311 polymorphisms and schizophrenia risk. But particularity, our result suggests the interaction, rs3924999-rs4673628 of NRG1 and ERBB4 genes surprisingly increases the risk of schizophrenia.Scopus© Citations 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, A systematic review and meta-analysis of neuroticism and anxiety during the COVID-19 pandemic(2023); ; ; INTRODUCTION: In response to the global impact of the COVID-19 pandemic, concerns about mental health, particularly anxiety levels, have become prominent. This study aims to explore the relationship between neuroticism, a personality trait associated with emotional instability, and anxiety during the COVID-19 outbreak. METHODS: A comprehensive literature search was conducted using the Cochrane Library, HINARI, Google Scholar, and PUBMED, resulting in the identification of 26 relevant papers. The study protocol has been registered with PROSPERO under the number CRD42023452418. Thorough meta-analysis was performed using Comprehensive Meta-Analysis V4 software. RESULTS: Meta-analysis revealed a significant positive relationship between anxiety and neuroticism, with 26 studies supporting this association (OR = 3.213, 95% CI 2.352 to 4.391). The findings underscore the importance of considering personality traits, particularly neuroticism, in understanding psychological responses to major global crises such as the COVID-19 epidemic. DISCUSSION: The observed connection between neuroticism and heightened anxiety levels emphasizes the need for targeted interventions, especially for individuals with high levels of neuroticism. Further research into potential therapeutic approaches for mitigating anxiety consequences in the context of a significant global catastrophe is warranted. SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/#CRD42023452418.Scopus© Citations 19 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Main characteristics of dermatoglypics associated with schizophrenia and its clinical subtypes(2021); ; Dermatoglypic patterns are extensively investigated to apply in disease-related risk assessment due to an obvious association between morphological and genetic characteristics. In the current study, we aimed to determine whether the fingerprint and palmar patterns vary between case population with schizophrenia and general population. A cross sectional study was conducted in people diagnosed with schizophrenia (cases) and a control population between 2016 and 2019. In this study, 252 people were participated. Ink and paper method was used to evaluate the difference of fingerprints palm prints between patients with schizophrenia and participants in control group.93 participants were analyzed in schizophrenic group and 142 participants were investigated in the control group. The percentage of arches on the right ring finger was significantly different between the schizophrenic patient group and control group (p = 0.011). The whorl pattern type (U-W-U-W-W-W-W-U-W-U) was dominantly observed in both of the schizophrenic patient group and control group. A-B ridge count in schizophrenic patient group and control group produced a markedly significant difference (p<0.05). Interestingly, a strong significant difference was produced in comparing of A-B ridge count in catatonic schizophrenia group with residual schizophrenia group (p<0.005). In comparison, index of pattern intensity in control group was slightly higher than that in schizophrenic patient group. Taking together, these results showed that the dermatoglypic characteristics might be a valuable tool to describe the nature of schizophrenia and its clinical subtypes and further studies are needed in clinical application.Scopus© Citations 7 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Шизофренийн эмнэлзүйн шинжүүдийг позитив ба негатив хам шинжийн үнэлгээ (PANSS)-ний сорилоор үнэлсэн нь(2025-10-20); Ж.СарантуяаҮндэслэл: Шизофренийн негатив болон позитив шинжүүд хэмээх онцлох шинж тэмдгүүд хослон илэрдэг эмнэлзүйтэй, архаг явцтай, дотоод шалтгаантай, сэтгэцийн хүнд эмгэг юм. Шизофрени голдуу өсвөр болон залуу насанд эхэлж хүний танин мэдэхүй, сэтгэхүй, сэтгэл хөдлөл зэрэг сэтгэцийн үйл ажиллагаа өөрчлөгдөн улмаар өдөр тутмын амьдралын үйл ажиллагаа болон нийгэмтэй дасан зохицох чадвар алдалтад хүргэдэг эмгэг юм. Шизофренийн оношилгоо, эмчилгээний явцыг үнэлэхэд позитив болон негатив шинжийн үнэлэх сорил (PANSS)-ыг өргөн хэрэглэдэг ба шинж тэмдэгийн хүндийн зэргийг тогтоодог. Уг сорилыг солиорлын шинж тэмдэгээр илэрдэг эмгэгүүдийг үнэлэх алтан стандарт гэж нэрлэдэг ба энэхүү үнэлгээний аргачлалыг ашиглан хийгдсэн судалгааны ажил олдохгүй байгаа нь энэхүү судалгааны ажлын үндэслэл боллоо. Зорилго: Шизофренийн эмнэлзүйн шинжүүдийг позитив ба негатив хам шинжийн үнэлгээ (PANSS)-ний сорилоор үнэлж, тэдгээрийн хүндийн зэргийг тогтоох. Арга, аргачлал: Бид сэтгэцийн эрүүл мэндийн үндэсний төвд 2016 оны 12 сараас 2019 оны 12 сар хүртэлх хугацаанд амбулаторийн идэвхтэй хяналтад хянагдаж буй шизофренитэй 102 хүнийг хамруулж, агшингийн загвараар гүйцэтгэсэн. Үр дүн: Судалгаанд нийт 20-66 насны 102 хүн хамрагдсанаас 51% (n=129) нь эмэгтэй, дундаж нас 40.0±12.0 жил байлаа. Позитив, негатив болон сэтгэцийн ерөнхий шинжүүдийн зэргийн дундаж нь хөнгөн болон дунд зэрэгт 21–24%, негатив шинжүүдийн маш хүнд зэрэг 23% байна. Энэ үзүүлэлт нь сэтгэл хөдлөлийн илэрхийлэл буурах, нийгмээс тусгаарлагдах, амьдралын идэвх сулрах зэрэг шинжүүд шизофренийн хүнд шатанд хүчтэй илэрдэг болохыг харуулж байна. Позитив шинжүүдийн хувьд хөнгөн болон дунд зэрэгт 15–24% байсан ба энэ нь өвчний эхэн үед хий үзэгдэл, дэмийрлийн шинжүүд тод илэрдэг боловч өвчин хүндрэх явцад харьцангуй буурдаг байна. Сэтгэцийн ерөнхий шинжүүдийн хувьд 12–22% байсан нь бүх зэрэгт тогтвортой илэрсэн. Дүгнэлт: Шизофренийн эмнэлзүйн эхэн үед позитив шинжүүд давамгай, харин өвчний хүнд шатанд негатив шинжүүд давамгайлж, сэтгэцийн ерөнхий шинжүүд бүх зэрэгт тогтвортой илэрч буй нь тодорхойлогдлоо.